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Mutation in murine coronavirus replication protein nsp4 alters assembly of double membrane vesicles
Coronaviruses are positive-strand RNA viruses that replicate in the cytoplasm of infected cells by generating a membrane-associated replicase complex. The replicase complex assembles on double membrane vesicles (DMVs). Here, we studied the role of a putative replicase anchor, nonstructural protein 4...
Autores principales: | Clementz, Mark A., Kanjanahaluethai, Amornrat, O'Brien, Timothy E., Baker, Susan C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443636/ https://www.ncbi.nlm.nih.gov/pubmed/18295294 http://dx.doi.org/10.1016/j.virol.2008.01.018 |
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