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GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors
BACKGROUND: GPR17 is a G-protein-coupled receptor located at intermediate phylogenetic position between two distinct receptor families: the P2Y and CysLT receptors for extracellular nucleotides and cysteinyl-LTs, respectively. We previously showed that GPR17 can indeed respond to both classes of end...
Autores principales: | Parravicini, Chiara, Ranghino, Graziella, Abbracchio, Maria P, Fantucci, Piercarlo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443813/ https://www.ncbi.nlm.nih.gov/pubmed/18533035 http://dx.doi.org/10.1186/1471-2105-9-263 |
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