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Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
BACKGROUND: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational methods that can distinguish disease-causing SAPs from neutral SAPs are needed. Many methods have been developed to distinguish...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2446391/ https://www.ncbi.nlm.nih.gov/pubmed/18588693 http://dx.doi.org/10.1186/1471-2105-9-297 |