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Impairment of Adolescent Hippocampal Plasticity in a Mouse Model for Alzheimer's Disease Precedes Disease Phenotype

The amyloid precursor protein (APP) was assumed to be an important neuron-morphoregulatory protein and plays a central role in Alzheimer's disease (AD) pathology. In the study presented here, we analyzed the APP-transgenic mouse model APP23 using 2-dimensional gel electrophoresis technology in...

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Detalles Bibliográficos
Autores principales:	Hartl, Daniela, Rohe, Michael, Mao, Lei, Staufenbiel, Matthias, Zabel, Claus, Klose, Joachim
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447155/ https://www.ncbi.nlm.nih.gov/pubmed/18648492 http://dx.doi.org/10.1371/journal.pone.0002759

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