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Individual-Based Modelling of Bacterial Ecologies and Evolution

This paper presents two approaches to the individual-based modelling of bacterial ecologies and evolution using computational tools. The first approach is a fine-grained model that is based on networks of interactivity between computational objects representing genes and proteins. The second approac...

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Detalles Bibliográficos
Autores principales: Vlachos, C., Gregory, R., Paton, R. C., Saunders, J. R., Wu, Q. H.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447324/
https://www.ncbi.nlm.nih.gov/pubmed/18629041
http://dx.doi.org/10.1002/cfg.368
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author Vlachos, C.
Gregory, R.
Paton, R. C.
Saunders, J. R.
Wu, Q. H.
author_facet Vlachos, C.
Gregory, R.
Paton, R. C.
Saunders, J. R.
Wu, Q. H.
author_sort Vlachos, C.
collection PubMed
description This paper presents two approaches to the individual-based modelling of bacterial ecologies and evolution using computational tools. The first approach is a fine-grained model that is based on networks of interactivity between computational objects representing genes and proteins. The second approach is a coarser-grained, agent-based model, which is designed to explore the evolvability of adaptive behavioural strategies in artificial bacteria represented by learning classifier systems. The structure and implementation of these computational models is discussed, and some results from simulation experiments are presented. Finally, the potential applications of the proposed models to the solution of real-world computational problems, and their use in improving our understanding of the mechanisms of evolution, are briefly outlined.
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spelling pubmed-24473242008-07-14 Individual-Based Modelling of Bacterial Ecologies and Evolution Vlachos, C. Gregory, R. Paton, R. C. Saunders, J. R. Wu, Q. H. Comp Funct Genomics Research Article This paper presents two approaches to the individual-based modelling of bacterial ecologies and evolution using computational tools. The first approach is a fine-grained model that is based on networks of interactivity between computational objects representing genes and proteins. The second approach is a coarser-grained, agent-based model, which is designed to explore the evolvability of adaptive behavioural strategies in artificial bacteria represented by learning classifier systems. The structure and implementation of these computational models is discussed, and some results from simulation experiments are presented. Finally, the potential applications of the proposed models to the solution of real-world computational problems, and their use in improving our understanding of the mechanisms of evolution, are briefly outlined. Hindawi Publishing Corporation 2004-02 /pmc/articles/PMC2447324/ /pubmed/18629041 http://dx.doi.org/10.1002/cfg.368 Text en Copyright © 2004 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Vlachos, C.
Gregory, R.
Paton, R. C.
Saunders, J. R.
Wu, Q. H.
Individual-Based Modelling of Bacterial Ecologies and Evolution
title Individual-Based Modelling of Bacterial Ecologies and Evolution
title_full Individual-Based Modelling of Bacterial Ecologies and Evolution
title_fullStr Individual-Based Modelling of Bacterial Ecologies and Evolution
title_full_unstemmed Individual-Based Modelling of Bacterial Ecologies and Evolution
title_short Individual-Based Modelling of Bacterial Ecologies and Evolution
title_sort individual-based modelling of bacterial ecologies and evolution
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447324/
https://www.ncbi.nlm.nih.gov/pubmed/18629041
http://dx.doi.org/10.1002/cfg.368
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