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Individual-Based Modelling of Bacterial Ecologies and Evolution
This paper presents two approaches to the individual-based modelling of bacterial ecologies and evolution using computational tools. The first approach is a fine-grained model that is based on networks of interactivity between computational objects representing genes and proteins. The second approac...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447324/ https://www.ncbi.nlm.nih.gov/pubmed/18629041 http://dx.doi.org/10.1002/cfg.368 |
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author | Vlachos, C. Gregory, R. Paton, R. C. Saunders, J. R. Wu, Q. H. |
author_facet | Vlachos, C. Gregory, R. Paton, R. C. Saunders, J. R. Wu, Q. H. |
author_sort | Vlachos, C. |
collection | PubMed |
description | This paper presents two approaches to the individual-based modelling of bacterial ecologies and evolution using computational tools. The first approach is a fine-grained model that is based on networks of interactivity between computational objects representing genes and proteins. The second approach is a coarser-grained, agent-based model, which is designed to explore the evolvability of adaptive behavioural strategies in artificial bacteria represented by learning classifier systems. The structure and implementation of these computational models is discussed, and some results from simulation experiments are presented. Finally, the potential applications of the proposed models to the solution of real-world computational problems, and their use in improving our understanding of the mechanisms of evolution, are briefly outlined. |
format | Text |
id | pubmed-2447324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-24473242008-07-14 Individual-Based Modelling of Bacterial Ecologies and Evolution Vlachos, C. Gregory, R. Paton, R. C. Saunders, J. R. Wu, Q. H. Comp Funct Genomics Research Article This paper presents two approaches to the individual-based modelling of bacterial ecologies and evolution using computational tools. The first approach is a fine-grained model that is based on networks of interactivity between computational objects representing genes and proteins. The second approach is a coarser-grained, agent-based model, which is designed to explore the evolvability of adaptive behavioural strategies in artificial bacteria represented by learning classifier systems. The structure and implementation of these computational models is discussed, and some results from simulation experiments are presented. Finally, the potential applications of the proposed models to the solution of real-world computational problems, and their use in improving our understanding of the mechanisms of evolution, are briefly outlined. Hindawi Publishing Corporation 2004-02 /pmc/articles/PMC2447324/ /pubmed/18629041 http://dx.doi.org/10.1002/cfg.368 Text en Copyright © 2004 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Vlachos, C. Gregory, R. Paton, R. C. Saunders, J. R. Wu, Q. H. Individual-Based Modelling of Bacterial Ecologies and Evolution |
title | Individual-Based Modelling of Bacterial Ecologies and Evolution |
title_full | Individual-Based Modelling of Bacterial Ecologies and Evolution |
title_fullStr | Individual-Based Modelling of Bacterial Ecologies and Evolution |
title_full_unstemmed | Individual-Based Modelling of Bacterial Ecologies and Evolution |
title_short | Individual-Based Modelling of Bacterial Ecologies and Evolution |
title_sort | individual-based modelling of bacterial ecologies and evolution |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447324/ https://www.ncbi.nlm.nih.gov/pubmed/18629041 http://dx.doi.org/10.1002/cfg.368 |
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