The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature

In general, it is not easy to specify a single sequence identity for each molecule name that appears in a pathway in the scientific literature. A molecule name may stand for concepts of various granularities, from concrete objects such as H-Ras and ERK1 to abstract concepts or categories such as Ras...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamamoto, Satoko, Asanuma, Takao, Takagi, Toshihisa, Fukuda, Ken Ichiro
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447435/
https://www.ncbi.nlm.nih.gov/pubmed/18629146
http://dx.doi.org/10.1002/cfg.432
_version_ 1782156938347282432
author Yamamoto, Satoko
Asanuma, Takao
Takagi, Toshihisa
Fukuda, Ken Ichiro
author_facet Yamamoto, Satoko
Asanuma, Takao
Takagi, Toshihisa
Fukuda, Ken Ichiro
author_sort Yamamoto, Satoko
collection PubMed
description In general, it is not easy to specify a single sequence identity for each molecule name that appears in a pathway in the scientific literature. A molecule name may stand for concepts of various granularities, from concrete objects such as H-Ras and ERK1 to abstract concepts or categories such as Ras and MAPK. Typically, the relations among molecule names derive a hierarchical structure; without a proper way to handle this knowledge, it becomes ever more difficult to develop a reliable pathway database. This paper describes an ontology that is designed to annotate molecules in the scientific literature on signal transduction pathways.
format Text
id pubmed-2447435
institution National Center for Biotechnology Information
language English
publishDate 2004
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-24474352008-07-14 The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature Yamamoto, Satoko Asanuma, Takao Takagi, Toshihisa Fukuda, Ken Ichiro Comp Funct Genomics Research Article In general, it is not easy to specify a single sequence identity for each molecule name that appears in a pathway in the scientific literature. A molecule name may stand for concepts of various granularities, from concrete objects such as H-Ras and ERK1 to abstract concepts or categories such as Ras and MAPK. Typically, the relations among molecule names derive a hierarchical structure; without a proper way to handle this knowledge, it becomes ever more difficult to develop a reliable pathway database. This paper describes an ontology that is designed to annotate molecules in the scientific literature on signal transduction pathways. Hindawi Publishing Corporation 2004 /pmc/articles/PMC2447435/ /pubmed/18629146 http://dx.doi.org/10.1002/cfg.432 Text en Copyright © 2004 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Yamamoto, Satoko
Asanuma, Takao
Takagi, Toshihisa
Fukuda, Ken Ichiro
The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature
title The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature
title_full The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature
title_fullStr The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature
title_full_unstemmed The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature
title_short The Molecule Role Ontology: An Ontology for Annotation of Signal Transduction Pathway Molecules in the Scientific Literature
title_sort molecule role ontology: an ontology for annotation of signal transduction pathway molecules in the scientific literature
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447435/
https://www.ncbi.nlm.nih.gov/pubmed/18629146
http://dx.doi.org/10.1002/cfg.432
work_keys_str_mv AT yamamotosatoko themoleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature
AT asanumatakao themoleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature
AT takagitoshihisa themoleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature
AT fukudakenichiro themoleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature
AT yamamotosatoko moleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature
AT asanumatakao moleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature
AT takagitoshihisa moleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature
AT fukudakenichiro moleculeroleontologyanontologyforannotationofsignaltransductionpathwaymoleculesinthescientificliterature

Ejemplares similares