KL-6 in acute lung injury: will it leave its mark?

Studies have indicated that measuring biochemical measures of epithelial injury in plasma and alveolar fluid may be useful in predicting outcome in acute lung injury. The present commentary briefly reviews the evidence supporting the use of these biochemical biomarkers of epithelial injury in acute...

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Detalles Bibliográficos
Autores principales: Shyamsundar, Murali, McAuley, Danny F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447564/
https://www.ncbi.nlm.nih.gov/pubmed/18423068
http://dx.doi.org/10.1186/cc6827
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author Shyamsundar, Murali
McAuley, Danny F
author_facet Shyamsundar, Murali
McAuley, Danny F
author_sort Shyamsundar, Murali
collection PubMed
description Studies have indicated that measuring biochemical measures of epithelial injury in plasma and alveolar fluid may be useful in predicting outcome in acute lung injury. The present commentary briefly reviews the evidence supporting the use of these biochemical biomarkers of epithelial injury in acute lung injury, and in particular KL-6, as well as their limitations. The article additionally proposes the need for physiological markers of epithelial function to complement current biochemical biomarkers.
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spelling pubmed-24475642008-07-10 KL-6 in acute lung injury: will it leave its mark? Shyamsundar, Murali McAuley, Danny F Crit Care Commentary Studies have indicated that measuring biochemical measures of epithelial injury in plasma and alveolar fluid may be useful in predicting outcome in acute lung injury. The present commentary briefly reviews the evidence supporting the use of these biochemical biomarkers of epithelial injury in acute lung injury, and in particular KL-6, as well as their limitations. The article additionally proposes the need for physiological markers of epithelial function to complement current biochemical biomarkers. BioMed Central 2008 2008-03-31 /pmc/articles/PMC2447564/ /pubmed/18423068 http://dx.doi.org/10.1186/cc6827 Text en Copyright © 2008 BioMed Central Ltd
spellingShingle Commentary
Shyamsundar, Murali
McAuley, Danny F
KL-6 in acute lung injury: will it leave its mark?
title KL-6 in acute lung injury: will it leave its mark?
title_full KL-6 in acute lung injury: will it leave its mark?
title_fullStr KL-6 in acute lung injury: will it leave its mark?
title_full_unstemmed KL-6 in acute lung injury: will it leave its mark?
title_short KL-6 in acute lung injury: will it leave its mark?
title_sort kl-6 in acute lung injury: will it leave its mark?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447564/
https://www.ncbi.nlm.nih.gov/pubmed/18423068
http://dx.doi.org/10.1186/cc6827
work_keys_str_mv AT shyamsundarmurali kl6inacutelunginjurywillitleaveitsmark
AT mcauleydannyf kl6inacutelunginjurywillitleaveitsmark

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