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Protein C as a surrogate end-point for clinical trials of sepsis
Identification of good surrogate end-points can greatly facilitate the design of clinical trials. Using data from PROWESS and ENHANCE, Shorr and colleagues explore the potential value of several plasma biomarkers for treatment trials of activated protein C for severe sepsis. Based on the framework p...
Autores principales: | Liu, Kathleen D, Matthay, Michael A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447596/ https://www.ncbi.nlm.nih.gov/pubmed/18492215 http://dx.doi.org/10.1186/cc6859 |
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