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GenoWatch: a disease gene mining browser for association study
A human gene association study often involves several genomic markers such as single nucleotide polymorphisms (SNPs) or short tandem repeat polymorphisms, and many statistically significant markers may be identified during the study. GenoWatch can efficiently extract up-to-date information about mul...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447740/ https://www.ncbi.nlm.nih.gov/pubmed/18440974 http://dx.doi.org/10.1093/nar/gkn214 |
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author | Chen, Yan-Hau Liu, Chuan-Kun Chang, Shu-Chuan Lin, Yi-Jung Tsai, Ming-Fang Chen, Yuan-Tsong Yao, Adam |
author_facet | Chen, Yan-Hau Liu, Chuan-Kun Chang, Shu-Chuan Lin, Yi-Jung Tsai, Ming-Fang Chen, Yuan-Tsong Yao, Adam |
author_sort | Chen, Yan-Hau |
collection | PubMed |
description | A human gene association study often involves several genomic markers such as single nucleotide polymorphisms (SNPs) or short tandem repeat polymorphisms, and many statistically significant markers may be identified during the study. GenoWatch can efficiently extract up-to-date information about multiple markers and their associated genes in batch mode from many relevant biological databases in real-time. The comprehensive gene information retrieved includes gene ontology, function, pathway, disease, related articles in PubMed and so on. Subsequent SNP functional impact analysis and primer design of a target gene for re-sequencing can also be done in a few clicks. The presentation of results has been carefully designed to be as intuitive as possible to all users. The GenoWatch is available at the website http://genepipe.ngc.sinica.edu.tw/genowatch |
format | Text |
id | pubmed-2447740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-24477402008-07-09 GenoWatch: a disease gene mining browser for association study Chen, Yan-Hau Liu, Chuan-Kun Chang, Shu-Chuan Lin, Yi-Jung Tsai, Ming-Fang Chen, Yuan-Tsong Yao, Adam Nucleic Acids Res Articles A human gene association study often involves several genomic markers such as single nucleotide polymorphisms (SNPs) or short tandem repeat polymorphisms, and many statistically significant markers may be identified during the study. GenoWatch can efficiently extract up-to-date information about multiple markers and their associated genes in batch mode from many relevant biological databases in real-time. The comprehensive gene information retrieved includes gene ontology, function, pathway, disease, related articles in PubMed and so on. Subsequent SNP functional impact analysis and primer design of a target gene for re-sequencing can also be done in a few clicks. The presentation of results has been carefully designed to be as intuitive as possible to all users. The GenoWatch is available at the website http://genepipe.ngc.sinica.edu.tw/genowatch Oxford University Press 2008-07-01 2008-04-25 /pmc/articles/PMC2447740/ /pubmed/18440974 http://dx.doi.org/10.1093/nar/gkn214 Text en © 2008 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Chen, Yan-Hau Liu, Chuan-Kun Chang, Shu-Chuan Lin, Yi-Jung Tsai, Ming-Fang Chen, Yuan-Tsong Yao, Adam GenoWatch: a disease gene mining browser for association study |
title | GenoWatch: a disease gene mining browser for association study |
title_full | GenoWatch: a disease gene mining browser for association study |
title_fullStr | GenoWatch: a disease gene mining browser for association study |
title_full_unstemmed | GenoWatch: a disease gene mining browser for association study |
title_short | GenoWatch: a disease gene mining browser for association study |
title_sort | genowatch: a disease gene mining browser for association study |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447740/ https://www.ncbi.nlm.nih.gov/pubmed/18440974 http://dx.doi.org/10.1093/nar/gkn214 |
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