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MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences
MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking into account the putative function of the sequences. In this perspective, MAGNOLIA is especially designe...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447753/ https://www.ncbi.nlm.nih.gov/pubmed/18515348 http://dx.doi.org/10.1093/nar/gkn321 |
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author | Fontaine, Arnaud de Monte, Antoine Touzet, Hélène |
author_facet | Fontaine, Arnaud de Monte, Antoine Touzet, Hélène |
author_sort | Fontaine, Arnaud |
collection | PubMed |
description | MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking into account the putative function of the sequences. In this perspective, MAGNOLIA is especially designed for sequences that are intended to be either protein-coding or structural RNAs. It extracts information from the similarities and differences in the data, and searches for a specific evolutionary pattern between sequences before aligning them. The alignment step then incorporates this information to achieve higher accuracy. The website is available at http://bioinfo.lifl.fr/magnolia. |
format | Text |
id | pubmed-2447753 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-24477532008-07-09 MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences Fontaine, Arnaud de Monte, Antoine Touzet, Hélène Nucleic Acids Res Articles MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking into account the putative function of the sequences. In this perspective, MAGNOLIA is especially designed for sequences that are intended to be either protein-coding or structural RNAs. It extracts information from the similarities and differences in the data, and searches for a specific evolutionary pattern between sequences before aligning them. The alignment step then incorporates this information to achieve higher accuracy. The website is available at http://bioinfo.lifl.fr/magnolia. Oxford University Press 2008-07-01 2008-05-30 /pmc/articles/PMC2447753/ /pubmed/18515348 http://dx.doi.org/10.1093/nar/gkn321 Text en © 2008 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Fontaine, Arnaud de Monte, Antoine Touzet, Hélène MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences |
title | MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences |
title_full | MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences |
title_fullStr | MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences |
title_full_unstemmed | MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences |
title_short | MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences |
title_sort | magnolia: multiple alignment of protein–coding and structural rna sequences |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447753/ https://www.ncbi.nlm.nih.gov/pubmed/18515348 http://dx.doi.org/10.1093/nar/gkn321 |
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