MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences

MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking into account the putative function of the sequences. In this perspective, MAGNOLIA is especially designe...

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Detalles Bibliográficos
Autores principales: Fontaine, Arnaud, de Monte, Antoine, Touzet, Hélène
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447753/
https://www.ncbi.nlm.nih.gov/pubmed/18515348
http://dx.doi.org/10.1093/nar/gkn321
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author Fontaine, Arnaud
de Monte, Antoine
Touzet, Hélène
author_facet Fontaine, Arnaud
de Monte, Antoine
Touzet, Hélène
author_sort Fontaine, Arnaud
collection PubMed
description MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking into account the putative function of the sequences. In this perspective, MAGNOLIA is especially designed for sequences that are intended to be either protein-coding or structural RNAs. It extracts information from the similarities and differences in the data, and searches for a specific evolutionary pattern between sequences before aligning them. The alignment step then incorporates this information to achieve higher accuracy. The website is available at http://bioinfo.lifl.fr/magnolia.
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spelling pubmed-24477532008-07-09 MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences Fontaine, Arnaud de Monte, Antoine Touzet, Hélène Nucleic Acids Res Articles MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking into account the putative function of the sequences. In this perspective, MAGNOLIA is especially designed for sequences that are intended to be either protein-coding or structural RNAs. It extracts information from the similarities and differences in the data, and searches for a specific evolutionary pattern between sequences before aligning them. The alignment step then incorporates this information to achieve higher accuracy. The website is available at http://bioinfo.lifl.fr/magnolia. Oxford University Press 2008-07-01 2008-05-30 /pmc/articles/PMC2447753/ /pubmed/18515348 http://dx.doi.org/10.1093/nar/gkn321 Text en © 2008 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Fontaine, Arnaud
de Monte, Antoine
Touzet, Hélène
MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences
title MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences
title_full MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences
title_fullStr MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences
title_full_unstemmed MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences
title_short MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences
title_sort magnolia: multiple alignment of protein–coding and structural rna sequences
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447753/
https://www.ncbi.nlm.nih.gov/pubmed/18515348
http://dx.doi.org/10.1093/nar/gkn321
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