ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data

ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of ‘complex functions’. A ‘Complex fun...

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Detalles Bibliográficos
Autores principales: Antonov, Alexey V., Schmidt, Thorsten, Wang, Yu, Mewes, Hans W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447768/
https://www.ncbi.nlm.nih.gov/pubmed/18460543
http://dx.doi.org/10.1093/nar/gkn239
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author Antonov, Alexey V.
Schmidt, Thorsten
Wang, Yu
Mewes, Hans W.
author_facet Antonov, Alexey V.
Schmidt, Thorsten
Wang, Yu
Mewes, Hans W.
author_sort Antonov, Alexey V.
collection PubMed
description ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of ‘complex functions’. A ‘Complex function’ is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. ProfCom provides a user friendly dialog-driven web page submission available for several model organisms and supports most available gene identifiers. In addition, the web service interface allows the submission of any kind of annotation data. ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/.
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spelling pubmed-24477682008-07-09 ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data Antonov, Alexey V. Schmidt, Thorsten Wang, Yu Mewes, Hans W. Nucleic Acids Res Articles ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of ‘complex functions’. A ‘Complex function’ is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. ProfCom provides a user friendly dialog-driven web page submission available for several model organisms and supports most available gene identifiers. In addition, the web service interface allows the submission of any kind of annotation data. ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/. Oxford University Press 2008-07-01 2008-05-06 /pmc/articles/PMC2447768/ /pubmed/18460543 http://dx.doi.org/10.1093/nar/gkn239 Text en © 2008 The Author(s) http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Antonov, Alexey V.
Schmidt, Thorsten
Wang, Yu
Mewes, Hans W.
ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data
title ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data
title_full ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data
title_fullStr ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data
title_full_unstemmed ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data
title_short ProfCom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data
title_sort profcom: a web tool for profiling the complex functionality of gene groups identified from high-throughput data
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447768/
https://www.ncbi.nlm.nih.gov/pubmed/18460543
http://dx.doi.org/10.1093/nar/gkn239
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