Computer-assisted assessment of the Human Epidermal Growth Factor Receptor 2 immunohistochemical assay in imaged histologic sections using a membrane isolation algorithm and quantitative analysis of positive controls

BACKGROUND: Breast cancers that overexpress the human epidermal growth factor receptor 2 (HER2) are eligible for effective biologically targeted therapies, such as trastuzumab. However, accurately determining HER2 overexpression, especially in immunohistochemically equivocal cases, remains a challen...

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Detalles Bibliográficos
Autores principales: Hall, Bonnie H, Ianosi-Irimie, Monica, Javidian, Parisa, Chen, Wenjin, Ganesan, Shridar, Foran, David J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447833/
https://www.ncbi.nlm.nih.gov/pubmed/18534031
http://dx.doi.org/10.1186/1471-2342-8-11

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