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Pituitary Changes in Prop1 Transgenic Mice: Hormone Producing Tumors and Signet-ring Type Gonadotropes

Prophet of Pit-1 (Prop1) is an early transcription factor that delays the appearance of gonadotropin in the developing pituitaries. Prop1 transgenic (Tg) mice have been shown to generate pituitary tumors that either produce TSH or are non-hormone producing. In our series of Prop1 Tg mice, only 5 out...

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Detalles Bibliográficos
Autores principales: Egashira, Noboru, Minematsu, Takeo, Miyai, Syunsuke, Takekoshi, Susumu, Camper, Sally A., Osamura, Robert Y.
Formato: Texto
Lenguaje:English
Publicado: Japan Society of Histochemistry and Cytochemistry 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447862/
https://www.ncbi.nlm.nih.gov/pubmed/18636109
http://dx.doi.org/10.1267/ahc.08007

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