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BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways
The histone acetyltransferase Tip60 regulates the apoptotic response to ultraviolet (UV) irradiation. A previously suggested mechanism for this regulation consists of the ability of Tip60 to coactivate transcription by the tumor suppressor p53. In this study, we show that Tip60 is required for the e...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447902/ https://www.ncbi.nlm.nih.gov/pubmed/18625847 http://dx.doi.org/10.1083/jcb.200712014 |