Cargando…

Thymidylate Synthase, Thymidine Phosphorylase and Orotate Phosphoribosyl Transferase Levels as Predictive Factors of Chemotherapy in Oral Squamous Cell Carcinoma

We conducted a clinicopathologic study on protein and mRNA levels of thymidylate synthase (TS), thymidine phosphorylase (TP) and orotate phosphoribosyl transferase (OPRT) using biopsy tissue specimens before treatment. The mRNA levels have been measured in tumor cells microdissected from paraffin-em...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ogiuchi, Yosuke, Maruoka, Yasubumi, Ando, Tomohiro, Kobayashi, Makio, Ogiuchi, Hideki
Formato:	Texto
Lenguaje:	English
Publicado:	Japan Society of Histochemistry and Cytochemistry 2008
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447914/ https://www.ncbi.nlm.nih.gov/pubmed/18636111 http://dx.doi.org/10.1267/ahc.08002

Ejemplares similares

Comment on “Influence of Orotate Phosphoribosyl Transferase Levels on Tumor Prognosis and Response to Chemotherapy”
por: Kapoor, Shailendra
Publicado: (2012)

Expression of thymidylate synthase and orotate phosphoribosyltransferase in thymic carcinoma
por: YOKOTA, KEISUKE, et al.
Publicado: (2012)

Clinical implications of thymidylate synthetase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase activity levels in colorectal carcinoma following radical resection and administration of adjuvant 5-FU chemotherapy
por: Ishikawa, Masashi, et al.
Publicado: (2008)

Overexpression of the Orotate Phosphoribosyl-Transferase Gene Enhances the Effect of 5-Fluorouracil in Head and Neck Squamous Cell Carcinoma In Vitro
por: Yasumatsu, Ryuji, et al.
Publicado: (2012)

Expression of the thymidine phosphorylase gene in epithelial ovarian cancer
por: Hata, K, et al.
Publicado: (1999)

Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis
por: Marchetti, S, et al.
Publicado: (2001)

Expression Levels of Thymidylate Synthase, Thymidylate Phosphorylase and Dihydropyrimidine Dehydrogenase in Head and Neck Squamous Cell Carcinoma: Preliminary Study
por: Aubry, K., et al.
Publicado: (2008)

Thymidine phosphorylase/platelet-derived endothelial cell growth factor is upregulated in advanced solid types of gastric cancer
por: Yoshikawa, T, et al.
Publicado: (1999)

Clinical significance of the thymidylate synthase, dihydropyrimidine dehydrogenase, and thymidine phosphorylase mRNA expressions in hepatocellular carcinoma patients receiving 5-fluorouracil-based transarterial chemoembolization treatment
por: Zhao, Hongyun, et al.
Publicado: (2013)

Down regulation by a low-zinc diet in gene expression of rat prostatic thymidylate synthase and thymidine kinase
por: Ishikawa, Yuko, et al.
Publicado: (2008)

The expression of thymidine phosphorylase correlates with angiogenesis and the efficacy of chemotherapy using fluorouracil derivatives in advanced gastric carcinoma
por: Saito, H, et al.
Publicado: (1999)

Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine
por: Uchida, Kazumi, et al.
Publicado: (2008)

An Evolutionary Analysis of Lateral Gene Transfer in Thymidylate Synthase Enzymes
por: Stern, Adi, et al.
Publicado: (2010)

The cytosol activity of thymidine phosphorylase in endometrial cancer
por: Miszczak-Zaborska, Elżbieta, et al.
Publicado: (2008)

Expression of Thymidine Phosphorylase in Human Gastric Carcinoma
por: Takebayashi, Yuji, et al.
Publicado: (1996)

Effect of Hammerhead Ribozyme against Human Thymidylate Synthase on the Cytotoxicity of Thymidylate Synthase Inhibitors
por: Kobayashi, Hiroyuki, et al.
Publicado: (1995)

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase
por: Di Gennaro, E, et al.
Publicado: (2010)

The ability to accumulate deoxyuridine triphosphate and cellular response to thymidylate synthase (TS) inhibition
por: Webley, S D, et al.
Publicado: (2001)

4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression
por: Tamura, Ryosuke, et al.
Publicado: (2014)

Induction of thymidine phosphorylase as a pharmacodynamic end-point in patients with advanced carcinoma treated with 5-fluorouracil, folinic acid and interferon alpha
por: Braybrooke, J P, et al.
Publicado: (2000)

Increased cytotoxicity and bystander effect of 5-fluorouracil and 5′-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase
por: Evrard, A, et al.
Publicado: (1999)

Nicotinamide Phosphoribosyl Transferase (Nampt) Is Required for De Novo Lipogenesis in Tumor Cells
por: Bowlby, Sarah C., et al.
Publicado: (2012)

Phosphoribosyl Pyrophosphate Amido Transferase: A New Prognostic Biomarker for Hepatocellular Carcinoma
por: Chu, Qingfei, et al.
Publicado: (2022)

Hypoxanthine guanine phosphoribosyl transferases SmHGPRTases functional roles in Schistosoma mansoni
por: Batista, Izabella Cristina Andrade, et al.
Publicado: (2022)

Modulation of thymidine phosphorylase by neoadjuvant chemotherapy in primary breast cancer
por: Toi, M, et al.
Publicado: (2004)

Structures of native human thymidine phosphorylase and in complex with 5-iodouracil
por: Mitsiki, Eirini, et al.
Publicado: (2009)

Thymidine Phosphorylase Gene Expression in Stage III Colorectal Cancer
por: Lindskog, Elinor B., et al.
Publicado: (2012)

Depletion of plasma thymidine results in growth retardation and mitochondrial myopathy in mice overexpressing human thymidine phosphorylase
por: Harada, Naomoto, et al.
Publicado: (2023)

Deoxyuridine triphosphatase (dUTPase) expression and sensitivity to the thymidylate synthase (TS) inhibitorD9331
por: Webley, S D, et al.
Publicado: (2000)

Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma
por: Wong, N A C S, et al.
Publicado: (2001)

Targeting thymidine phosphorylase as a potential therapy for bone loss associated with periprosthetic osteolysis
por: Matsumae, Gen, et al.
Publicado: (2021)

Non-cell autonomous effect of neuronal nicotinamide phosphoribosyl transferase on the function of neuromuscular junctions
por: Lundt, Samuel, et al.
Publicado: (2020)

Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas
por: Yin, Jianxing, et al.
Publicado: (2023)

Prolonged and enhanced suppression of thymidylate synthase by weekly 24-h infusion of high-dose 5-fluorouracil
por: Yeh, K-H, et al.
Publicado: (2000)

The Expression of Thymidine Phosphorylase in Cancer-infiltrating Inflammatory Cells in Stomach Cancer
por: Jang, Joung Soon, et al.
Publicado: (2007)

Research development of the relationship between thymidine phosphorylase expression and colorectal carcinoma
por: Ye, Dian-Jun, et al.
Publicado: (2013)

Biochemical abnormalities in a patient with thymidine phosphorylase deficiency with fatal outcome
por: Bakker, Jaap A., et al.
Publicado: (2010)

Liver as a Source for Thymidine Phosphorylase Replacement in Mitochondrial Neurogastrointestinal Encephalomyopathy
por: Boschetti, Elisa, et al.
Publicado: (2014)

Possible role of thymidine phosphorylase in gynecological tumors as an individualized treatment strategy
por: Shida, Masako, et al.
Publicado: (2016)

Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy
por: Levene, Michelle, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tbdvkbi8ldc6o8rncvuge0pimo