Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies

Fifty patients whose sera contained a speckled antinuclear antibody (ANA) were interviewed and examined to determine if there was any relationship between their clinical manifestations and the presence of certain serological markers. The results suggest that speckled ANA is usually found in patients...

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Detalles Bibliográficos
Autores principales: McMillan, S A, Fay, Anne C, Taggart, A J, McCrea, J D, Roberts, S D, Boyd, M W J, Nelson, Jennifer K, Haire, Margaret
Formato: Texto
Lenguaje:English
Publicado: 1986
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448365/
https://www.ncbi.nlm.nih.gov/pubmed/3492803
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author McMillan, S A
Fay, Anne C
Taggart, A J
McCrea, J D
Roberts, S D
Boyd, M W J
Nelson, Jennifer K
Haire, Margaret
author_facet McMillan, S A
Fay, Anne C
Taggart, A J
McCrea, J D
Roberts, S D
Boyd, M W J
Nelson, Jennifer K
Haire, Margaret
author_sort McMillan, S A
collection PubMed
description Fifty patients whose sera contained a speckled antinuclear antibody (ANA) were interviewed and examined to determine if there was any relationship between their clinical manifestations and the presence of certain serological markers. The results suggest that speckled ANA is usually found in patients with definite connective tissue diseases, but a significant minority have incomplete or early stages of these diseases. Characterisation of the antibody to extractable nuclear antigen (ENA) and other serological markers does not normally assist in making a clinical diagnosis, but the detection of a speckled ANA should prompt further investigation and careful follow-up.
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spelling pubmed-24483652008-07-10 Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies McMillan, S A Fay, Anne C Taggart, A J McCrea, J D Roberts, S D Boyd, M W J Nelson, Jennifer K Haire, Margaret Ulster Med J Articles Fifty patients whose sera contained a speckled antinuclear antibody (ANA) were interviewed and examined to determine if there was any relationship between their clinical manifestations and the presence of certain serological markers. The results suggest that speckled ANA is usually found in patients with definite connective tissue diseases, but a significant minority have incomplete or early stages of these diseases. Characterisation of the antibody to extractable nuclear antigen (ENA) and other serological markers does not normally assist in making a clinical diagnosis, but the detection of a speckled ANA should prompt further investigation and careful follow-up. 1986-10 /pmc/articles/PMC2448365/ /pubmed/3492803 Text en
spellingShingle Articles
McMillan, S A
Fay, Anne C
Taggart, A J
McCrea, J D
Roberts, S D
Boyd, M W J
Nelson, Jennifer K
Haire, Margaret
Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies
title Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies
title_full Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies
title_fullStr Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies
title_full_unstemmed Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies
title_short Clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies
title_sort clinical and laboratory characteristics of patients with speckled pattern antinuclear antibodies
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448365/
https://www.ncbi.nlm.nih.gov/pubmed/3492803
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