Cargando…

Comparison of Mycobacterium Tuberculosis Genomes Reveals Frequent Deletions in a 20 kb Variable Region in Clinical Isolates

The Mycobacterium tuberculosis complex is associated with a remarkably low level of structural gene polymorphism. As part of a search for alternative forms of genetic variation that may act as a source of biological diversity in M. tuberculosis, we have identified a region of the genome that is high...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ho, Timothy B. L., Robertson, Brian D., Taylor, G. Michael, Shaw, Rory J., Young, Douglas B.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2000
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448390/ https://www.ncbi.nlm.nih.gov/pubmed/11119304 http://dx.doi.org/10.1002/1097-0061(200012)17:4<272::AID-YEA48>3.0.CO;2-2

Ejemplares similares

Enhancer deletions of the SHOX gene as a frequent cause of short stature: the essential role of a 250 kb downstream regulatory domain
por: Chen, J, et al.
Publicado: (2009)

A deletion in the RD105 region confers resistance to multiple drugs in Mycobacterium tuberculosis
por: Qin, Lianhua, et al.
Publicado: (2019)

Targeted deletion of a 170-kb cluster of LINE-1 repeats and implications for regional control
por: Soares, Miguel L., et al.
Publicado: (2018)

Determination of variable region sequences from hybridoma immunoglobulins that target Mycobacterium tuberculosis virulence factors
por: Foreman, Hui-Chen Chang, et al.
Publicado: (2021)

Structure and variation of CRISPR and CRISPR-flanking regions in deleted-direct repeat region Mycobacterium tuberculosis complex strains
por: Freidlin, Paul Jeffrey, et al.
Publicado: (2017)

Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion
por: Duncan, Carla, et al.
Publicado: (2017)

Successful Rescue of Synthetic AcMNPV with a ~17 kb Deletion in the C1 Region of the Genome
por: Guo, Yijia, et al.
Publicado: (2022)

TRPV1 dysfunction in cystinosis patients harboring the homozygous 57 kb deletion
por: Buntinx, L., et al.
Publicado: (2016)

Molecular Strain Typing of Mycobacterium tuberculosis: a Review of Frequently Used Methods
por: Ei, Phyu Win, et al.
Publicado: (2016)

Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis
por: Shelton, Catherine D., et al.
Publicado: (2021)

Detection of Common Deletional of α-Thalassemia 3.7 Kb from Metropolitan Region of Manaus, Amazonas, Brazil
por: Anselmo, Fernanda Cozendey, et al.
Publicado: (2021)

Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma
por: Abnet, Christian C, et al.
Publicado: (2004)

A 20‐kb lineage‐specific genomic region tames virulence in pathogenic amphidiploid Verticillium longisporum
por: Harting, Rebekka, et al.
Publicado: (2021)

The Interplay of Human and Mycobacterium Tuberculosis Genomic Variability
por: Correa-Macedo, Wilian, et al.
Publicado: (2019)

Hypermethylation of genomic 3.3-kb repeats is frequent event in HPV-positive cervical cancer
por: Katargin, Alexey N, et al.
Publicado: (2009)

A novel 8.57‐kb deletion of the upstream region of PRKAR1A in a family with Carney complex
por: Ito, Shin, et al.
Publicado: (2022)

Identification of small RNAs in Mycobacterium tuberculosis
por: Arnvig, Kristine B, et al.
Publicado: (2009)

Effective Amplification of 20-kb DNA by Reverse Transcription PCR()
por: Thiel, Volker, et al.
Publicado: (1997)

Deletion of cyp125 Confers Increased Sensitivity to Azoles in Mycobacterium tuberculosis
por: Carroll, Paul, et al.
Publicado: (2015)

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for EsxW Beijing variant in Vietnam
por: Holt, Kathryn E, et al.
Publicado: (2018)

The impact of frequently neglected model violations on bacterial recombination rate estimation: a case study in Mycobacterium canettii and Mycobacterium tuberculosis
por: Sabin, Susanna, et al.
Publicado: (2022)

Genomic Variability of Mycobacterium tuberculosis Strains of the Euro-American Lineage Based on Large Sequence Deletions and 15-Locus MIRU-VNTR Polymorphism
por: Rindi, Laura, et al.
Publicado: (2014)

Specialized Transduction Designed for Precise High-Throughput Unmarked Deletions in Mycobacterium tuberculosis
por: Jain, Paras, et al.
Publicado: (2014)

Rapid molecular diagnostics of large deletional β(0)-thalassemia (3.5 kb and 45 kb) using colorimetric LAMP in various thalassemia genotypes
por: Tepakhan, Wanicha, et al.
Publicado: (2021)

Evidence for Highly Variable, Region-Specific Patterns of T-Cell Epitope Mutations Accumulating in Mycobacterium tuberculosis Strains
por: Ramaiah, Arunachalam, et al.
Publicado: (2019)

Kearns‐Sayre syndrome case. Novel 5,9 kb mtDNA deletion
por: Grigalionienė, Kristina, et al.
Publicado: (2022)

Identification of region of difference and H37Rv-related deletion in Mycobacterium tuberculosis complex by structural variant detection and genome assembly
por: Liu, Zhuochong, et al.
Publicado: (2022)

Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
por: Gallia, Gary L., et al.
Publicado: (2018)

Neuropsychological phenotype of a patient with a de novo 970 kb interstitial deletion in the distal 16p11.2 region
por: Egger, Jos I M, et al.
Publicado: (2014)

Correction: Genomic Variability of Mycobacterium tuberculosis Strains of the Euro-American Lineage Based on Large Sequence Deletions and 15-Locus MIRU-VNTR Polymorphism
Publicado: (2014)

Frequent gene deletions in potentially malignant oral lesions.
por: Emilion, G., et al.
Publicado: (1996)

Analysis of meiotic recombination in 22q11.2, a region that frequently undergoes deletions and duplications
por: Torres-Juan, Laura, et al.
Publicado: (2007)

Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts
por: Orgeur, Mickael, et al.
Publicado: (2021)

In-depth Analysis of IS6110 Genomic Variability in the Mycobacterium tuberculosis Complex
por: Comín, Jessica, et al.
Publicado: (2022)

Insertion and deletion evolution reflects antibiotics selection pressure in a Mycobacterium tuberculosis outbreak
por: Godfroid, Maxime, et al.
Publicado: (2020)

The Immunogenicity and Safety of Mycobacterium tuberculosis-mosR-Based Double Deletion Strain in Mice
por: Hildebrand, Rachel E., et al.
Publicado: (2023)

Analysis of whiB7 in Mycobacterium tuberculosis reveals novel AT-hook deletion mutations
por: Davies-Bolorunduro, Olabisi Flora, et al.
Publicado: (2023)

A 556 kb deletion in the downstream region of the PAX6 gene causes familial aniridia and other eye anomalies in a Chinese family
por: Cheng, Fang, et al.
Publicado: (2011)

MPT64 Protein from Mycobacterium tuberculosis Inhibits Apoptosis of Macrophages through NF-kB-miRNA21-Bcl-2 Pathway
por: Wang, Qingmin, et al.
Publicado: (2014)

When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions
por: Bradbury, Andrew R. M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_b6h5n9gq8t6en39ktcekfobpfg