Learning About Gene Regulatory Networks From Gene Deletion Experiments

Gene regulatory networks are a major focus of interest in molecular biology. A crucial question is how complex regulatory systems are encoded and controlled by the genome. Three recent publications have raised the question of what can be learned about gene regulatory networks from microarray experim...

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Detalles Bibliográficos
Autores principales: Schlitt, Thomas, Brazma, Alvis
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448417/
https://www.ncbi.nlm.nih.gov/pubmed/18629255
http://dx.doi.org/10.1002/cfg.220
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author Schlitt, Thomas
Brazma, Alvis
author_facet Schlitt, Thomas
Brazma, Alvis
author_sort Schlitt, Thomas
collection PubMed
description Gene regulatory networks are a major focus of interest in molecular biology. A crucial question is how complex regulatory systems are encoded and controlled by the genome. Three recent publications have raised the question of what can be learned about gene regulatory networks from microarray experiments on gene deletion mutants. Using this indirect approach, topological features such as connectivity and modularity have been studied.
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spelling pubmed-24484172008-07-14 Learning About Gene Regulatory Networks From Gene Deletion Experiments Schlitt, Thomas Brazma, Alvis Comp Funct Genomics Research Article Gene regulatory networks are a major focus of interest in molecular biology. A crucial question is how complex regulatory systems are encoded and controlled by the genome. Three recent publications have raised the question of what can be learned about gene regulatory networks from microarray experiments on gene deletion mutants. Using this indirect approach, topological features such as connectivity and modularity have been studied. Hindawi Publishing Corporation 2002-12 /pmc/articles/PMC2448417/ /pubmed/18629255 http://dx.doi.org/10.1002/cfg.220 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Schlitt, Thomas
Brazma, Alvis
Learning About Gene Regulatory Networks From Gene Deletion Experiments
title Learning About Gene Regulatory Networks From Gene Deletion Experiments
title_full Learning About Gene Regulatory Networks From Gene Deletion Experiments
title_fullStr Learning About Gene Regulatory Networks From Gene Deletion Experiments
title_full_unstemmed Learning About Gene Regulatory Networks From Gene Deletion Experiments
title_short Learning About Gene Regulatory Networks From Gene Deletion Experiments
title_sort learning about gene regulatory networks from gene deletion experiments
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448417/
https://www.ncbi.nlm.nih.gov/pubmed/18629255
http://dx.doi.org/10.1002/cfg.220
work_keys_str_mv AT schlittthomas learningaboutgeneregulatorynetworksfromgenedeletionexperiments
AT brazmaalvis learningaboutgeneregulatorynetworksfromgenedeletionexperiments

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