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Harvesting the Mouse Genome
The sequencing of the black 6 mouse (strain C57Bl/6) has reached an important juncture. The BAC fingerprint map is almost complete, the BACs have been endsequenced and a seven-fold coverage whole-genome shotgun has been assembled. Now the BAC-by-BAC sequencing phase is under way and in-depth compara...
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448424/ https://www.ncbi.nlm.nih.gov/pubmed/18629261 http://dx.doi.org/10.1002/cfg.198 |
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author | Botcherby, Marc |
author_facet | Botcherby, Marc |
author_sort | Botcherby, Marc |
collection | PubMed |
description | The sequencing of the black 6 mouse (strain C57Bl/6) has reached an important juncture. The BAC fingerprint map is almost complete, the BACs have been endsequenced and a seven-fold coverage whole-genome shotgun has been assembled. Now the BAC-by-BAC sequencing phase is under way and in-depth comparative analysis can be carried out on regions that have been the subject of targeted sequencing. This paper reviews the progress so far and looks forward to the promises of finished sequence. |
format | Text |
id | pubmed-2448424 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-24484242008-07-14 Harvesting the Mouse Genome Botcherby, Marc Comp Funct Genomics Research Article The sequencing of the black 6 mouse (strain C57Bl/6) has reached an important juncture. The BAC fingerprint map is almost complete, the BACs have been endsequenced and a seven-fold coverage whole-genome shotgun has been assembled. Now the BAC-by-BAC sequencing phase is under way and in-depth comparative analysis can be carried out on regions that have been the subject of targeted sequencing. This paper reviews the progress so far and looks forward to the promises of finished sequence. Hindawi Publishing Corporation 2002-08 /pmc/articles/PMC2448424/ /pubmed/18629261 http://dx.doi.org/10.1002/cfg.198 Text en Copyright © 2002 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Botcherby, Marc Harvesting the Mouse Genome |
title | Harvesting the Mouse Genome |
title_full | Harvesting the Mouse Genome |
title_fullStr | Harvesting the Mouse Genome |
title_full_unstemmed | Harvesting the Mouse Genome |
title_short | Harvesting the Mouse Genome |
title_sort | harvesting the mouse genome |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448424/ https://www.ncbi.nlm.nih.gov/pubmed/18629261 http://dx.doi.org/10.1002/cfg.198 |
work_keys_str_mv | AT botcherbymarc harvestingthemousegenome |