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Hepatitis delta virus infection in Northern Ireland 1970-1989.

The incidence of hepatitis delta virus (HDV) infection in Northern Ireland (1970-1989) was tested by enzyme linked immunosorbent assay in 401 hepatitis B surface antigen (HBsAg) positive sera. Hepatitis delta antigen (HDAg) was tested in 388 patients and antibody to delta antigen (anti-HD) in 401 pa...

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Detalles Bibliográficos
Autores principales: Curran, R. A., O'Neill, H. J., Connolly, J. H.
Formato: Texto
Lenguaje:English
Publicado: Ulster Medical Society 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448660/
https://www.ncbi.nlm.nih.gov/pubmed/1785149
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author Curran, R. A.
O'Neill, H. J.
Connolly, J. H.
author_facet Curran, R. A.
O'Neill, H. J.
Connolly, J. H.
author_sort Curran, R. A.
collection PubMed
description The incidence of hepatitis delta virus (HDV) infection in Northern Ireland (1970-1989) was tested by enzyme linked immunosorbent assay in 401 hepatitis B surface antigen (HBsAg) positive sera. Hepatitis delta antigen (HDAg) was tested in 388 patients and antibody to delta antigen (anti-HD) in 401 patients. Four patients (1.03%) were HDAg positive. Nine patients (2.24%) were positive for anti-HD and after acid pre-treatment of sera from eight of these patients, five were positive for HDAg. The overall incidence of HDV markers was 3.27%, which reflects the low incidence in HBsAg carriers in Northern Ireland (who were in high risk groups for delta hepatitis). The use of acid treatment of the sera to break up antigen/antibody complexes has been a useful technological improvement in the identification of this virus.
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spelling pubmed-24486602008-07-10 Hepatitis delta virus infection in Northern Ireland 1970-1989. Curran, R. A. O'Neill, H. J. Connolly, J. H. Ulster Med J Research Article The incidence of hepatitis delta virus (HDV) infection in Northern Ireland (1970-1989) was tested by enzyme linked immunosorbent assay in 401 hepatitis B surface antigen (HBsAg) positive sera. Hepatitis delta antigen (HDAg) was tested in 388 patients and antibody to delta antigen (anti-HD) in 401 patients. Four patients (1.03%) were HDAg positive. Nine patients (2.24%) were positive for anti-HD and after acid pre-treatment of sera from eight of these patients, five were positive for HDAg. The overall incidence of HDV markers was 3.27%, which reflects the low incidence in HBsAg carriers in Northern Ireland (who were in high risk groups for delta hepatitis). The use of acid treatment of the sera to break up antigen/antibody complexes has been a useful technological improvement in the identification of this virus. Ulster Medical Society 1991-10 /pmc/articles/PMC2448660/ /pubmed/1785149 Text en
spellingShingle Research Article
Curran, R. A.
O'Neill, H. J.
Connolly, J. H.
Hepatitis delta virus infection in Northern Ireland 1970-1989.
title Hepatitis delta virus infection in Northern Ireland 1970-1989.
title_full Hepatitis delta virus infection in Northern Ireland 1970-1989.
title_fullStr Hepatitis delta virus infection in Northern Ireland 1970-1989.
title_full_unstemmed Hepatitis delta virus infection in Northern Ireland 1970-1989.
title_short Hepatitis delta virus infection in Northern Ireland 1970-1989.
title_sort hepatitis delta virus infection in northern ireland 1970-1989.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448660/
https://www.ncbi.nlm.nih.gov/pubmed/1785149
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