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Large-scale gene-expression studies and the challenge of multiple sclerosis
In multiple sclerosis, a complex neurodegenerative disorder, a combination of genetic and environmental factors results in inflammation and myelin damage. Recent transcription-profiling studies have found distinct gene-expression patterns in diseased tissue; such large-scale studies at different sta...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2002
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC244911/ https://www.ncbi.nlm.nih.gov/pubmed/12372148 http://dx.doi.org/10.1186/gb-2002-3-10-reviews1027 |
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author | Baranzini, Sergio E Hauser, Stephen L |
author_facet | Baranzini, Sergio E Hauser, Stephen L |
author_sort | Baranzini, Sergio E |
collection | PubMed |
description | In multiple sclerosis, a complex neurodegenerative disorder, a combination of genetic and environmental factors results in inflammation and myelin damage. Recent transcription-profiling studies have found distinct gene-expression patterns in diseased tissue; such large-scale studies at different stages of the disease are contributing to understanding multiple sclerosis and developing effective therapy. |
format | Text |
id | pubmed-244911 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2002 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-2449112003-11-06 Large-scale gene-expression studies and the challenge of multiple sclerosis Baranzini, Sergio E Hauser, Stephen L Genome Biol Minireview In multiple sclerosis, a complex neurodegenerative disorder, a combination of genetic and environmental factors results in inflammation and myelin damage. Recent transcription-profiling studies have found distinct gene-expression patterns in diseased tissue; such large-scale studies at different stages of the disease are contributing to understanding multiple sclerosis and developing effective therapy. BioMed Central 2002 2002-09-16 /pmc/articles/PMC244911/ /pubmed/12372148 http://dx.doi.org/10.1186/gb-2002-3-10-reviews1027 Text en Copyright © 2002 BioMed Central Ltd |
spellingShingle | Minireview Baranzini, Sergio E Hauser, Stephen L Large-scale gene-expression studies and the challenge of multiple sclerosis |
title | Large-scale gene-expression studies and the challenge of multiple sclerosis |
title_full | Large-scale gene-expression studies and the challenge of multiple sclerosis |
title_fullStr | Large-scale gene-expression studies and the challenge of multiple sclerosis |
title_full_unstemmed | Large-scale gene-expression studies and the challenge of multiple sclerosis |
title_short | Large-scale gene-expression studies and the challenge of multiple sclerosis |
title_sort | large-scale gene-expression studies and the challenge of multiple sclerosis |
topic | Minireview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC244911/ https://www.ncbi.nlm.nih.gov/pubmed/12372148 http://dx.doi.org/10.1186/gb-2002-3-10-reviews1027 |
work_keys_str_mv | AT baranzinisergioe largescalegeneexpressionstudiesandthechallengeofmultiplesclerosis AT hauserstephenl largescalegeneexpressionstudiesandthechallengeofmultiplesclerosis |