CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers

CD133/prominin-1 is a pentaspan transmembrane glycoprotein overexpressed in various solid tumours including colorectal and glioblastomas. CD133 was found here to be highly expressed in ⩾50% of pancreatic, gastric and intrahepatic cholangiocarcinomas. Quantitative flow cytometric analysis showed that...

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Detalles Bibliográficos
Autores principales: Smith, L M, Nesterova, A, Ryan, M C, Duniho, S, Jonas, M, Anderson, M, Zabinski, R F, Sutherland, M K, Gerber, H-P, Van Orden, K L, Moore, P A, Ruben, S M, Carter, P J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453027/
https://www.ncbi.nlm.nih.gov/pubmed/18542072
http://dx.doi.org/10.1038/sj.bjc.6604437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453027/
https://www.ncbi.nlm.nih.gov/pubmed/18542072
http://dx.doi.org/10.1038/sj.bjc.6604437

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