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Purification and characterization of recombinant human renin for X-ray crystallization studies
BACKGROUND: The renin-angiotensin-aldosterone system (RAS) cascade is a major target for the clinical management of hypertension. Although inhibitors of various components of this cascade have been developed successfully, development of renin inhibitors has proven to be problematic. The development...
Autores principales: | Wu, Zhongren, Cappiello, Maria G, Scott, Boyd B, Bukhtiyarov, Yuri, McGeehan, Gerard M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453115/ https://www.ncbi.nlm.nih.gov/pubmed/18582379 http://dx.doi.org/10.1186/1471-2091-9-19 |
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