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Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity
BACKGROUND: Rapamycin, an inhibitor of mammalian target of Rapamycin (mTOR), is an immunosuppressive agent that has anti-proliferative effects on some tumors. However, the role of Rapamycin-induced immune suppression on tumor progression has not been examined. METHODS: We developed a transplantation...
Autores principales: | Svirshchevskaya, Elena V, Mariotti, Jacopo, Wright, Mollie H, Viskova, Natalia Y, Telford, William, Fowler, Daniel H, Varticovski, Lyuba |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453140/ https://www.ncbi.nlm.nih.gov/pubmed/18570671 http://dx.doi.org/10.1186/1471-2407-8-176 |
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