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A Novel Role of the NRF2 Transcription Factor in the Regulation of Arsenite-Mediated Keratin 16 Gene Expression in Human Keratinocytes
BACKGROUND: Inorganic sodium arsenite (iAs) is a ubiquitous environmental contaminant and is associated with an increased risk of skin hyperkeratosis and cancer. OBJECTIVES: We investigated the molecular mechanisms underlying the regulation of the keratin 16 (K16) gene by iAs in the human keratinocy...
Autores principales: | Endo, Hitoshi, Sugioka, Yoshihiko, Nakagi, Yoshihiko, Saijo, Yasuaki, Yoshida, Takahiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453154/ https://www.ncbi.nlm.nih.gov/pubmed/18629308 http://dx.doi.org/10.1289/ehp.10696 |
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