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Conserving, Distributing and Managing Genetically Modified Mouse Lines by Sperm Cryopreservation
BACKGROUND: Sperm from C57BL/6 mice are difficult to cryopreserve and recover. Yet, the majority of genetically modified (GM) lines are maintained on this genetic background. METHODOLOGY/PRINCIPAL FINDINGS: Reported here is the development of an easily implemented method that consistently yields fer...
Autores principales: | Ostermeier, G. Charles, Wiles, Michael V., Farley, Jane S., Taft, Robert A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453316/ https://www.ncbi.nlm.nih.gov/pubmed/18665210 http://dx.doi.org/10.1371/journal.pone.0002792 |
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