Evidence of Henipavirus Infection in West African Fruit Bats

Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%,...

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Autores principales: Hayman, David T. S., Suu-Ire, Richard, Breed, Andrew C., McEachern, Jennifer A., Wang, Linfa, Wood, James L. N., Cunningham, Andrew A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453319/
https://www.ncbi.nlm.nih.gov/pubmed/18648649
http://dx.doi.org/10.1371/journal.pone.0002739
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author Hayman, David T. S.
Suu-Ire, Richard
Breed, Andrew C.
McEachern, Jennifer A.
Wang, Linfa
Wood, James L. N.
Cunningham, Andrew A.
author_facet Hayman, David T. S.
Suu-Ire, Richard
Breed, Andrew C.
McEachern, Jennifer A.
Wang, Linfa
Wood, James L. N.
Cunningham, Andrew A.
author_sort Hayman, David T. S.
collection PubMed
description Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95% confidence interval: 27–51%) and Hendra (22%, 95% CI: 11–33%) viruses. Virus neutralization tests further confirmed seropositivity for 30% (7/23) of Luminex positive serum samples. Our results indicate that henipavirus is present within West Africa.
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spelling pubmed-24533192008-07-23 Evidence of Henipavirus Infection in West African Fruit Bats Hayman, David T. S. Suu-Ire, Richard Breed, Andrew C. McEachern, Jennifer A. Wang, Linfa Wood, James L. N. Cunningham, Andrew A. PLoS One Research Article Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95% confidence interval: 27–51%) and Hendra (22%, 95% CI: 11–33%) viruses. Virus neutralization tests further confirmed seropositivity for 30% (7/23) of Luminex positive serum samples. Our results indicate that henipavirus is present within West Africa. Public Library of Science 2008-07-23 /pmc/articles/PMC2453319/ /pubmed/18648649 http://dx.doi.org/10.1371/journal.pone.0002739 Text en Hayman et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Hayman, David T. S.
Suu-Ire, Richard
Breed, Andrew C.
McEachern, Jennifer A.
Wang, Linfa
Wood, James L. N.
Cunningham, Andrew A.
Evidence of Henipavirus Infection in West African Fruit Bats
title Evidence of Henipavirus Infection in West African Fruit Bats
title_full Evidence of Henipavirus Infection in West African Fruit Bats
title_fullStr Evidence of Henipavirus Infection in West African Fruit Bats
title_full_unstemmed Evidence of Henipavirus Infection in West African Fruit Bats
title_short Evidence of Henipavirus Infection in West African Fruit Bats
title_sort evidence of henipavirus infection in west african fruit bats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453319/
https://www.ncbi.nlm.nih.gov/pubmed/18648649
http://dx.doi.org/10.1371/journal.pone.0002739
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