Cargando…
MAPK Kinase Kinase-1 Is Essential for Cytokine-Induced c-Jun NH(2)-Terminal Kinase and Nuclear Factor-κB Activation in Human Pancreatic Islet Cells
OBJECTIVE—The transcription factor nuclear factor-κB (NF-κB) and the mitogen-activated protein kinases (MAPKs) c-Jun NH(2)-terminal kinase (JNK) 1/2 are known to play decisive roles in cytokine-induced damage of rodent β-cells. The upstream events by which these factors are activated in response to...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Diabetes Association
2008
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453607/ https://www.ncbi.nlm.nih.gov/pubmed/18420486 http://dx.doi.org/10.2337/db07-1670 |