Cargando…

Association Analysis of Type 2 Diabetes Loci in Type 1 Diabetes

OBJECTIVE—To search for a possible association of type 1 diabetes with 10 validated type 2 diabetes loci, i.e., PPARG, KCNJ11, WFS1, HNF1B, IDE/HHEX, SLC30A8, CDKAL1, CDKN2A/B, IGF2BP2, and FTO/RPGRIP1L. RESEARCH DESIGN AND METHODS—Two European population samples were studied: 1) one case-control co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Hui-Qi, Grant, Struan F.A., Bradfield, Jonathan P., Kim, Cecilia, Frackelton, Edward, Hakonarson, Hakon, Polychronakos, Constantin
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453613/ https://www.ncbi.nlm.nih.gov/pubmed/18426861 http://dx.doi.org/10.2337/db08-0270

Ejemplares similares

Examination of All Type 2 Diabetes GWAS Loci Reveals HHEX-IDE as a Locus Influencing Pediatric BMI
por: Zhao, Jianhua, et al.
Publicado: (2010)

Follow-Up Analysis of Genome-Wide Association Data Identifies Novel Loci for Type 1 Diabetes
por: Grant, Struan F.A., et al.
Publicado: (2009)

A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci
por: Bradfield, Jonathan P., et al.
Publicado: (2011)

Rare Genetic Variants of Large Effect Influence Risk of Type 1 Diabetes
por: Forgetta, Vincenzo, et al.
Publicado: (2020)

Examination of Type 2 Diabetes Loci Implicates CDKAL1 as a Birth Weight Gene
por: Zhao, Jianhua, et al.
Publicado: (2009)

From Disease Association to Risk Assessment: An Optimistic View from Genome-Wide Association Studies on Type 1 Diabetes
por: Wei, Zhi, et al.
Publicado: (2009)

Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
por: Qu, Hui-Qi, et al.
Publicado: (2021)

Genome-wide association study of the age of onset of type 1 diabetes reveals HTATIP2 as a novel T cell regulator
por: Cardinale, Christopher J., et al.
Publicado: (2023)

Obesity-susceptibility loci and the tails of the pediatric BMI distribution
por: Mitchell, Jonathan A., et al.
Publicado: (2013)

Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes
por: Mishra, Rajashree, et al.
Publicado: (2017)

Insights into non-autoimmune type 1 diabetes with 13 novel loci in low polygenic risk score patients
por: Qu, Jingchun, et al.
Publicado: (2021)

Allelic Expression Imbalance: Tipping the Scales to Elucidate the Function of Type 2 Diabetes–Associated Loci
por: McCormack, Shana E., et al.
Publicado: (2015)

Large Copy-Number Variations Are Enriched in Cases With Moderate to Extreme Obesity
por: Wang, Kai, et al.
Publicado: (2010)

Genome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations
por: Dajani, Rana, et al.
Publicado: (2017)

The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature
por: Zhao, Jianhua, et al.
Publicado: (2010)

The Dynamic Origins of Type 1 Diabetes
por: Leslie, R. David, et al.
Publicado: (2018)

The TCF7L2 Locus: A Genetic Window Into the Pathogenesis of Type 1 and Type 2 Diabetes
por: Grant, Struan F.A.
Publicado: (2019)

Assessing the functional consequence of loss of function variants using electronic medical record and large-scale genomics consortium efforts
por: Sleiman, Patrick, et al.
Publicado: (2014)

Mendelian randomization study of obesity and type 2 diabetes in hospitalized COVID-19 patients
por: Qu, Hui-Qi, et al.
Publicado: (2022)

Duplication of the SLIT3 Locus on 5q35.1 Predisposes to Major Depressive Disorder
por: Glessner, Joseph T., et al.
Publicado: (2010)

Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data
por: Johnson, Matthew E, et al.
Publicado: (2014)

The TCF7L2 locus and type 1 diabetes
por: Qu, Hui-Qi, et al.
Publicado: (2007)

Imputation of TPMT defective alleles for the identification of patients with high-risk phenotypes
por: Almoguera, Berta, et al.
Publicado: (2014)

Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program
por: Hivert, Marie-France, et al.
Publicado: (2011)

The missense variation landscape of FTO, MC4R and TMEM18 in obese children of African ancestry
por: Deliard, Sandra, et al.
Publicado: (2013)

Association of the BANK 1 R61H variant with systemic lupus erythematosus in Americans of European and African ancestry
por: Grant, Struan FA, et al.
Publicado: (2009)

Transferability and Fine Mapping of Type 2 Diabetes Loci in African Americans: The Candidate Gene Association Resource Plus Study
por: Ng, Maggie C.Y., et al.
Publicado: (2013)

Target Genes of Autism Risk Loci in Brain Frontal Cortex
por: Sun, Yan, et al.
Publicado: (2019)

Genes Involved in Type 1 Diabetes: An Update
por: Bakay, Marina, et al.
Publicado: (2013)

Identification of Target Genes at Juvenile Idiopathic Arthritis GWAS Loci in Human Neutrophils
por: Li, Junyi, et al.
Publicado: (2019)

Replication Study for the Association Between Four Loci Identified by a Genome-Wide Association Study on European American Subjects With Type 1 Diabetes and Susceptibility to Diabetic Nephropathy in Japanese Subjects With Type 2 Diabetes
por: Maeda, Shiro, et al.
Publicado: (2010)

Evaluation of Genome Wide Association Study Associated Type 2 Diabetes Susceptibility Loci in Sub Saharan Africans
por: Adeyemo, Adebowale A., et al.
Publicado: (2015)

Fine Mapping of Type 2 Diabetes Susceptibility Loci
por: Morris, Andrew P.
Publicado: (2014)

Physical Interactions and Expression Quantitative Traits Loci Identify Regulatory Connections for Obesity and Type 2 Diabetes Associated SNPs
por: Fadason, Tayaza, et al.
Publicado: (2017)

Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men
por: Stančáková, Alena, et al.
Publicado: (2011)

Identifying novel genetic loci associated with polycystic ovary syndrome based on its shared genetic architecture with type 2 diabetes
por: Li, Xiaoyi, et al.
Publicado: (2022)

Association Analysis of the FTO Gene with Obesity in Children of Caucasian and African Ancestry Reveals a Common Tagging SNP
por: Grant, Struan F. A., et al.
Publicado: (2008)

Genetics of Obesity and Type 2 Diabetes in African Americans
por: McCormack, Shana, et al.
Publicado: (2013)

Prioritising Causal Genes at Type 2 Diabetes Risk Loci
por: Grotz, Antje K., et al.
Publicado: (2017)

Transcriptome Profiling of Human Ulcerative Colitis Mucosa Reveals Altered Expression of Pathways Enriched in Genetic Susceptibility Loci
por: Cardinale, Christopher J., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_botsv44i241257ap8h61pg2t23