Cargando…

Improved Vascular Engraftment and Graft Function After Inhibition of the Angiostatic Factor Thrombospondin-1 in Mouse Pancreatic Islets

OBJECTIVE—Insufficient development of a new intra-islet capillary network after transplantation may be one contributing factor to the failure of islet grafts in clinical transplantation. The present study tested the hypothesis that the angiostatic factor thrombospondin-1 (TSP-1), which is normally p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Olerud, Johan, Johansson, Magnus, Lawler, Jack, Welsh, Nils, Carlsson, Per-Ola
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453615/ https://www.ncbi.nlm.nih.gov/pubmed/18420490 http://dx.doi.org/10.2337/db07-0724

Ejemplares similares

Thrombospondin-1: An Islet Endothelial Cell Signal of Importance for β-Cell Function
por: Olerud, Johan, et al.
Publicado: (2011)

Increased Numbers of Low-Oxygenated Pancreatic Islets After Intraportal Islet Transplantation
por: Olsson, Richard, et al.
Publicado: (2011)

Clinical and Experimental Pancreatic Islet Transplantation to Striated Muscle: Establishment of a Vascular System Similar to That in Native Islets
por: Christoffersson, Gustaf, et al.
Publicado: (2010)

Sustained Beta-Cell Dysfunction but Normalized Islet Mass in Aged Thrombospondin-1 Deficient Mice
por: Drott, Carl Johan, et al.
Publicado: (2012)

Markedly Decreased Blood Perfusion of Pancreatic Islets Transplanted Intraportally Into the Liver: Disruption of Islet Integrity Necessary for Islet Revascularization
por: Henriksnäs, Johanna, et al.
Publicado: (2012)

Viral Infection of Engrafted Human Islets Leads to Diabetes
por: Gallagher, Glen R., et al.
Publicado: (2015)

Bioengineering with Endothelial Progenitor Cells Improves the Vascular Engraftment of Transplanted Human Islets
por: Grapensparr, Liza, et al.
Publicado: (2018)

Quantification of β-Cell Mass in Intramuscular Islet Grafts Using Radiolabeled Exendin-4
por: Espes, Daniel, et al.
Publicado: (2016)

Endothelial Progenitor Cell Cotransplantation Enhances Islet Engraftment by Rapid Revascularization
por: Kang, Shinae, et al.
Publicado: (2012)

Mesenchymal Stem Cells Enhance Allogeneic Islet Engraftment in Nonhuman Primates
por: Berman, Dora M., et al.
Publicado: (2010)

Unsurpassed Intrahepatic Islet Engraftment – the Quest for New Sites for Beta Cell Replacement
por: Liljebäck, Hanna, et al.
Publicado: (2019)

Donor Islet Endothelial Cells in Pancreatic Islet Revascularization
por: Nyqvist, Daniel, et al.
Publicado: (2011)

Donor bone marrow–derived macrophage engraftment into the central nervous system of patients following allogeneic transplantion
por: Loeb, Anisha M., et al.
Publicado: (2023)

Alemtuzumab and CXCL9 levels predict likelihood of sustained engraftment after reduced-intensity conditioning HCT
por: Geerlinks, Ashley V., et al.
Publicado: (2023)

Glucose and Inflammation Control Islet Vascular Density and β-Cell Function in NOD Mice: Control of Islet Vasculature and Vascular Endothelial Growth Factor by Glucose
por: Akirav, Eitan M., et al.
Publicado: (2011)

Inducible Sbds deletion impairs bone marrow niche capacity to engraft donor bone marrow after transplantation
por: Zha, Ji, et al.
Publicado: (2022)

Activated pancreatic stellate cells can impair pancreatic islet function in mice
por: Zang, Guangxiang, et al.
Publicado: (2015)

Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes
por: Shah, Payal, et al.
Publicado: (2016)

A Theranostic Small Interfering RNA Nanoprobe Protects Pancreatic Islet Grafts From Adoptively Transferred Immune Rejection
por: Wang, Ping, et al.
Publicado: (2012)

Anti-inflammatory Approach With Early Double Cytokine Blockade (IL-1β and TNF-α) Is Safe and Facilitates Engraftment in Islet Allotransplantation
por: Onaca, Nicholas, et al.
Publicado: (2020)

Correction: Angiopoetin-2 Signals Do Not Mediate the Hypervascularization of Islets in Type 2 Diabetes
por: Shah, Payal, et al.
Publicado: (2023)

Local Autoantigen Expression as Essential Gatekeeper of Memory T-Cell Recruitment to Islet Grafts in Diabetic Hosts
por: Alkemade, Gonnie M., et al.
Publicado: (2013)

Influence of microenvironment on engraftment of transplanted β-cells
por: Carlsson, Per-Ola
Publicado: (2011)

Protection of Pancreatic Islets Using Theranostic Silencing Nanoparticles in a Baboon Model of Islet Transplantation
por: Pomposelli, Thomas, et al.
Publicado: (2020)

Induction of Chimerism Permits Low-Dose Islet Grafts in the Liver or Pancreas to Reverse Refractory Autoimmune Diabetes
por: Zhang, Chunyan, et al.
Publicado: (2010)

Pancreatic β-Cell–Derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation
por: Yoshimatsu, Gumpei, et al.
Publicado: (2017)

Full chimaeric CAR.CIK from patients engrafted after allogeneic haematopoietic cell transplant: Feasibility, anti‐leukaemic potential and alloreactivity across major human leukocyte antigen barriers
por: Circosta, Paola, et al.
Publicado: (2022)

Pancreatic Duct Cells in Human Islet Cell Preparations Are a Source of Angiogenic Cytokines Interleukin-8 and Vascular Endothelial Growth Factor
por: Movahedi, Babak, et al.
Publicado: (2008)

Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices
por: Johansson, Ulrika, et al.
Publicado: (2015)

Irisin—A Pancreatic Islet Hormone
por: Norman, Daniel, et al.
Publicado: (2022)

Graft rejection markers in children undergoing hematopoietic cell transplant for bone marrow failure
por: Sabulski, Anthony, et al.
Publicado: (2021)

Pancreatic Grafts from Pediatric Donors Do Not Appear to Grow After Transplantation into Adults
por: Christensen, Kaerli, et al.
Publicado: (2018)

T-replete HLA-matched grafts vs T-depleted HLA-mismatched grafts in inborn errors of immunity
por: Lum, Su Han, et al.
Publicado: (2022)

Dipeptidyl Peptidase IV Inhibition With MK0431 Improves Islet Graft Survival in Diabetic NOD Mice Partially via T-Cell Modulation
por: Kim, Su-Jin, et al.
Publicado: (2009)

The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro
por: Wang, Xuan, et al.
Publicado: (2018)

Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
por: Silva, Diego G., et al.
Publicado: (2011)

The interaction of Thrombospondins with extracellular matrix proteins
por: Tan, Kemin, et al.
Publicado: (2009)

Rituximab Selectively Suppresses Specific Islet Antibodies
por: Yu, Liping, et al.
Publicado: (2011)

Cytomegalovirus gastroenteritis in patients with acute graft-versus-host disease
por: Akahoshi, Yu, et al.
Publicado: (2022)

Impact of cryopreservation and transit times of allogeneic grafts on hematopoietic and immune reconstitution
por: Maurer, Katie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_phrlfnpv2apktcngps6qdk7peq