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Blockade of α4 Integrin Signaling Ameliorates the Metabolic Consequences of High-Fat Diet–Induced Obesity

OBJECTIVE—Many prevalent diseases of advanced societies, such as obesity-induced type 2 diabetes, are linked to indolent mononuclear cell–dependent inflammation. We previously proposed that blockade of α4 integrin signaling can inhibit inflammation while limiting mechanism-based toxicities of loss o...

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Detalles Bibliográficos
Autores principales:	Féral, Chloé C., Neels, Jaap G., Kummer, Christiane, Slepak, Marina, Olefsky, Jerrold M., Ginsberg, Mark H.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Obesity Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453617/ https://www.ncbi.nlm.nih.gov/pubmed/18426864 http://dx.doi.org/10.2337/db07-1751

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