TNF inhibits production of stromal cell-derived factor 1 by bone stromal cells and increases osteoclast precursor mobilization from bone marrow to peripheral blood

INTRODUCTION: The objective of the present study was to investigate the role of the stromal cell-derived factor 1 (SDF-1)/CXCR4 axis in TNF-induced mobilization of osteoclast precursors (OCPs) from bone marrow. METHODS: OCPs were generated from bone marrow cells of TNF-transgenic mice or wild-type m...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Guo, Ruolin, Schwarz, Edward M, Boyce, Brendan F, Xing, Lianping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453755/
https://www.ncbi.nlm.nih.gov/pubmed/18371213
http://dx.doi.org/10.1186/ar2391

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