Dysfunctional interferon-α production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus

BACKGROUND: It is well known that interferon (IFN)-α is important to the pathogenesis of systemic lupus erythematosus (SLE). However, several reports have indicated that the number of IFN-α producing cells are decreased or that their function is defective in patients with SLE. We studied the functio...

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Autores principales: Kwok, Seung-Ki, Lee, June-Yong, Park, Se-Ho, Cho, Mi-La, Min, So-Youn, Park, Sung-Hwan, Kim, Ho-Youn, Cho, Young-Gyu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453773/
https://www.ncbi.nlm.nih.gov/pubmed/18321389
http://dx.doi.org/10.1186/ar2382

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