Methylation of class II transactivator gene promoter IV is not associated with susceptibility to Multiple Sclerosis

BACKGROUND: Multiple sclerosis (MS) is a complex trait in which alleles at or near the class II loci HLA-DRB1 and HLA-DQB1 contribute significantly to genetic risk. The MHC class II transactivator (MHC2TA) is the master controller of expression of class II genes, and methylation of the promoter of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramagopalan, Sreeram V, Dyment, David A, Morrison, Katie M, Herrera, Blanca M, DeLuca, Gabriele C, Lincoln, Matthew R, Orton, Sarah M, Handunnetthi, Lahiru, Chao, Michael J, Sadovnick, A Dessa, Ebers, George C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464579/
https://www.ncbi.nlm.nih.gov/pubmed/18606010
http://dx.doi.org/10.1186/1471-2350-9-63

Ejemplares similares

Ejemplares similares