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Regulating Factors of PrP(res) Glycosylation in Creutzfeldt-Jakob Disease - Implications for the Dissemination and the Diagnosis of Human Prion Strains

OBJECTIVE: The glycoprofile of pathological prion protein (PrP(res)) is widely used as a diagnosis marker in Creutzfeldt-Jakob disease (CJD) and is thought to vary in a strain-specific manner. However, that the same glycoprofile of PrP(res) always accumulates in the whole brain of one individual has...

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Detalles Bibliográficos
Autores principales: Levavasseur, Etienne, Laffont-Proust, Isabelle, Morain, Émilie, Faucheux, Baptiste A., Privat, Nicolas, Peoc'h, Katell, Sazdovitch, Véronique, Brandel, Jean-Philippe, Hauw, Jean-Jacques, Haïk, Stéphane
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464735/
https://www.ncbi.nlm.nih.gov/pubmed/18665216
http://dx.doi.org/10.1371/journal.pone.0002786