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Chronic heart failure in Japan: Implications of the CHART studies

The prognosis of patients with chronic heart failure (CHF) still remains poor, despite the recent advances in medical and surgical treatment. Furthermore, CHF is a major public health problem in most industrialized countries where the elderly population is rapidly increasing. Although the prevalence...

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Detalles Bibliográficos
Autores principales: Shiba, Nobuyuki, Shimokawa, Hiroaki
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464764/
https://www.ncbi.nlm.nih.gov/pubmed/18629369
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author Shiba, Nobuyuki
Shimokawa, Hiroaki
author_facet Shiba, Nobuyuki
Shimokawa, Hiroaki
author_sort Shiba, Nobuyuki
collection PubMed
description The prognosis of patients with chronic heart failure (CHF) still remains poor, despite the recent advances in medical and surgical treatment. Furthermore, CHF is a major public health problem in most industrialized countries where the elderly population is rapidly increasing. Although the prevalence and mortality of CHF used to be relatively low in Japan, the disorder has been markedly increasing due to the rapid aging of the society and the Westernization of lifestyle that facilitates the development of coronary artery disease. The Chronic Heart Failure Analysis and Registry in the Tohoku District (CHART)-1 study was one of the largest cohorts in Japan. The study has clarified the characteristics and prognosis of Japanese patients with CHF, demonstrating that their prognosis was similarly poor compared with those in Western countries. However, we still need evidence for the prevention and treatment of CHF based on the large cohort studies or randomized treatment trials in the Japanese population. Since the strategy for CHF management is now changing from treatment to prevention, a larger-size prospective cohort, called the CHART-2 study, has been initiated to evaluate the risk factors of CHF in Japan. This review summarizes the current status of CHF studies in Japan and discusses their future perspectives.
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spelling pubmed-24647642008-07-15 Chronic heart failure in Japan: Implications of the CHART studies Shiba, Nobuyuki Shimokawa, Hiroaki Vasc Health Risk Manag Review The prognosis of patients with chronic heart failure (CHF) still remains poor, despite the recent advances in medical and surgical treatment. Furthermore, CHF is a major public health problem in most industrialized countries where the elderly population is rapidly increasing. Although the prevalence and mortality of CHF used to be relatively low in Japan, the disorder has been markedly increasing due to the rapid aging of the society and the Westernization of lifestyle that facilitates the development of coronary artery disease. The Chronic Heart Failure Analysis and Registry in the Tohoku District (CHART)-1 study was one of the largest cohorts in Japan. The study has clarified the characteristics and prognosis of Japanese patients with CHF, demonstrating that their prognosis was similarly poor compared with those in Western countries. However, we still need evidence for the prevention and treatment of CHF based on the large cohort studies or randomized treatment trials in the Japanese population. Since the strategy for CHF management is now changing from treatment to prevention, a larger-size prospective cohort, called the CHART-2 study, has been initiated to evaluate the risk factors of CHF in Japan. This review summarizes the current status of CHF studies in Japan and discusses their future perspectives. Dove Medical Press 2008-02 /pmc/articles/PMC2464764/ /pubmed/18629369 Text en © 2008 Shiba and Shimokawa, publisher and licensee Dove Medical Press Ltd.
spellingShingle Review
Shiba, Nobuyuki
Shimokawa, Hiroaki
Chronic heart failure in Japan: Implications of the CHART studies
title Chronic heart failure in Japan: Implications of the CHART studies
title_full Chronic heart failure in Japan: Implications of the CHART studies
title_fullStr Chronic heart failure in Japan: Implications of the CHART studies
title_full_unstemmed Chronic heart failure in Japan: Implications of the CHART studies
title_short Chronic heart failure in Japan: Implications of the CHART studies
title_sort chronic heart failure in japan: implications of the chart studies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464764/
https://www.ncbi.nlm.nih.gov/pubmed/18629369
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