Cargando…

Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia

Mostrar otras versiones (1)

Estrogen modifies human emotion and cognition and impacts symptoms of schizophrenia. We hypothesized that the variation in the estrogen receptor alpha (ESR1) gene and cortical ESR1 mRNA is associated with schizophrenia. In a small case–control genetic association analysis of postmortem brain tissue,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weickert, Cynthia Shannon, Miranda-Angulo, Ana L., Wong, Jenny, Perlman, William R., Ward, Sarah E., Radhakrishna, Vakkalanka, Straub, Richard E., Weinberger, Daniel R., Kleinman, Joel E.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2465798/ https://www.ncbi.nlm.nih.gov/pubmed/18424448 http://dx.doi.org/10.1093/hmg/ddn130

Ejemplares similares

Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia
por: Shannon Weickert, Cynthia, et al.
Publicado: (2012)

Functional Polymorphisms in PRODH Are Associated with Risk and Protection for Schizophrenia and Fronto-Striatal Structure and Function
por: Kempf, Lucas, et al.
Publicado: (2008)

Selective Estrogen Receptor Modulation Increases Hippocampal Activity during Probabilistic Association Learning in Schizophrenia
por: Kindler, Jochen, et al.
Publicado: (2015)

15. ON THE ROAD TO CURING SCHIZOPHRENIA
por: Weickert, Cynthia Shannon
Publicado: (2018)

Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder
por: Sinclair, Duncan, et al.
Publicado: (2012)

Raloxifene Improves Cognition in Schizophrenia: Spurious Result or Valid Effect?
por: Weickert, Thomas W., et al.
Publicado: (2017)

Relationship between somatostatin and death receptor expression in the orbital frontal cortex in schizophrenia: a postmortem brain mRNA study
por: Joshi, Dipesh, et al.
Publicado: (2015)

Neuroinflammation in schizophrenia: the role of nuclear factor kappa B
por: Murphy, Caitlin E., et al.
Publicado: (2021)

Adjunctive selective estrogen receptor modulator increases neural activity in the hippocampus and inferior frontal gyrus during emotional face recognition in schizophrenia
por: Ji, E, et al.
Publicado: (2016)

Glucocorticoid Receptor 1B and 1C mRNA Transcript Alterations in Schizophrenia and Bipolar Disorder, and Their Possible Regulation by GR Gene Variants
por: Sinclair, Duncan, et al.
Publicado: (2012)

Increases in [(3)H]Muscimol and [(3)H]Flumazenil Binding in the Dorsolateral Prefrontal Cortex in Schizophrenia Are Linked to α4 and γ2S mRNA Levels Respectively
por: Verdurand, Mathieu, et al.
Publicado: (2013)

Decreased BDNF and TrkB mRNA expression in multiple cortical areas of patients with schizophrenia and mood disorders
por: Ray, M T, et al.
Publicado: (2014)

Cell proliferation is reduced in the hippocampus in schizophrenia
por: Allen, Katherine M, et al.
Publicado: (2015)

Gene Expression Analysis Implicates a Death Receptor Pathway in Schizophrenia Pathology
por: Catts, Vibeke Sørensen, et al.
Publicado: (2012)

Overexpression of Neuregulin 1 Type III Confers Hippocampal mRNA Alterations and Schizophrenia-Like Behaviors in Mice
por: Olaya, Juan C, et al.
Publicado: (2018)

40.1 INFLAMMATORY CYTOKINES ARE ELEVATED IN THE MIDBRAIN IN SCHIZOPHRENIA
por: Purves-Tyson, Tertia, et al.
Publicado: (2018)

White matter neuron biology and neuropathology in schizophrenia
por: Duchatel, Ryan J., et al.
Publicado: (2019)

Mapping DNA methylation across development, genotype, and schizophrenia in the human frontal cortex
por: Jaffe, Andrew E., et al.
Publicado: (2015)

Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients
por: Mostaid, Md Shaki, et al.
Publicado: (2017)

Testosterone Is Inversely Related to Brain Activity during Emotional Inhibition in Schizophrenia
por: Vercammen, Ans, et al.
Publicado: (2013)

Interactions of human truncated DISC1 proteins: implications for schizophrenia
por: Newburn, E N, et al.
Publicado: (2011)

Genetic and epigenetic analysis of schizophrenia in blood—a no-brainer?
por: Jaffe, Andrew E., et al.
Publicado: (2016)

Peripheral NF-κB dysregulation in people with schizophrenia drives inflammation: putative anti-inflammatory functions of NF-κB kinases
por: Murphy, Caitlin E., et al.
Publicado: (2022)

Biomarkers in Schizophrenia: A Brief Conceptual Consideration
por: Weickert, Cynthia S., et al.
Publicado: (2013)

Potential Role of Oestrogen Modulation in the Treatment of Neurocognitive Deficits in Schizophrenia
por: Weickert, Thomas W., et al.
Publicado: (2016)

Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia
por: Lipska, Barbara K., et al.
Publicado: (2006)

Gene expression in the prefrontal cortex during adolescence: implications for the onset of schizophrenia
por: Harris, Laura W, et al.
Publicado: (2009)

M174. REDUCED CHEMOKINE SIGNALLING CAPACITY IS ASSOCIATED WITH INHIBITORY INTERNEURON DYSFUNCTION IN SUBCORTICAL BRAIN REGIONS IN SCHIZOPHRENIA AND BIPOLAR DISORDER
por: Weissleder, Christin, et al.
Publicado: (2020)

O11.2. ELEVATION OF MACROPHAGE-RELATED TRANSCRIPTS IN THE MIDBRAIN IN SCHIZOPHRENIA
por: Purves-Tyson, Tertia, et al.
Publicado: (2020)

Rethinking schizophrenia in the context of normal neurodevelopment
por: Catts, Vibeke S., et al.
Publicado: (2013)

M62. PERIPHERAL INFLAMMATION MARKERS IDENTIFY SUBSET OF PATIENTS WITH SCHIZOPHRENIA AND RELATED PSYCHOSES WHO HAVE INTELLECTUAL DECLINE FROM PREMORBID LEVELS
por: Weickert, Thomas, et al.
Publicado: (2020)

Cannabinoid receptor CNR1 expression and DNA methylation in human prefrontal cortex, hippocampus and caudate in brain development and schizophrenia
por: Tao, Ran, et al.
Publicado: (2020)

Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia
por: Radulescu, Eugenia, et al.
Publicado: (2023)

Dopaminergic therapy removal differentially effects learning in schizophrenia and Parkinson’s disease
por: Weickert, Thomas W., et al.
Publicado: (2013)

Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia
por: Purves-Tyson, Tertia D., et al.
Publicado: (2021)

Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging
por: Weissleder, Christin, et al.
Publicado: (2019)

Transcriptomic Analysis Shows Decreased Cortical Expression of NR4A1, NR4A2 and RXRB in Schizophrenia and Provides Evidence for Nuclear Receptor Dysregulation
por: Corley, Susan M., et al.
Publicado: (2016)

O1.5. ICAM-1 IS INCREASED IN BRAIN AND PERIPHERAL LEVELS OF SOLUBLE ICAM-1 IS RELATED TO COGNITIVE DEFICITS IN SCHIZOPHRENIA
por: Weickert, Thomas, et al.
Publicado: (2018)

The effects of preventative cannabidiol in a male neuregulin 1 mouse model of schizophrenia
por: Visini, Gabriela, et al.
Publicado: (2022)

Perceptual Category Judgment Deficits are Related to Prefrontal Decision Making Abnormalities in Schizophrenia
por: Weickert, Thomas W., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_gvus6aeuhj5k6g9h5o6d1ec6ic