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A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

Background:Activated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is embryonic or perinatal lethal. Objective:We...

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Detalles Bibliográficos
Autores principales:	TAI, S J, HERZOG, R W, MARGARITIS, P, ARRUDA, V R, CHU, K, GOLDEN, J A, LABOSKY, P A, HIGH, K A
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2008
Materias:	Coagulation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2471867/ https://www.ncbi.nlm.nih.gov/pubmed/18036190 http://dx.doi.org/10.1111/j.1538-7836.2008.02849.x

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