Detection of Catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE

BACKGROUND: Systemic lupus erythematosus (SLE) is a multifactorial disorder characterized by the presence of autoantibodies. We and others have implicated free radical mediated peroxidative damage in the pathogenesis of SLE. Since harmful free radical products are formed during this oxidative proces...

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Detalles Bibliográficos
Autores principales: D'souza, Anil, Kurien, Biji T, Rodgers, Rosalie, Shenoi, Jaideep, Kurono, Sadamu, Matsumoto, Hiroyuki, Hensley, Kenneth, Nath, Swapan K, Scofield, R Hal
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474584/
https://www.ncbi.nlm.nih.gov/pubmed/18606005
http://dx.doi.org/10.1186/1471-2350-9-62

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