Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells

BACKGROUND: Drug resistance is a major concern in cancer therapy. Here, we investigate the clinical potential of the second mitochondria-derived activator of caspase (Smac/DIABLO) in enhancing the apoptosis-inducing potential of commonly used anticancer drugs (paclitaxel, doxorubicin, etoposide, tam...

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Detalles Bibliográficos
Autores principales: Fandy, Tamer E, Shankar, Sharmila, Srivastava, Rakesh K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474652/
https://www.ncbi.nlm.nih.gov/pubmed/18590557
http://dx.doi.org/10.1186/1476-4598-7-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474652/
https://www.ncbi.nlm.nih.gov/pubmed/18590557
http://dx.doi.org/10.1186/1476-4598-7-60

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