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Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells

BACKGROUND: Drug resistance is a major concern in cancer therapy. Here, we investigate the clinical potential of the second mitochondria-derived activator of caspase (Smac/DIABLO) in enhancing the apoptosis-inducing potential of commonly used anticancer drugs (paclitaxel, doxorubicin, etoposide, tam...

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Detalles Bibliográficos
Autores principales:	Fandy, Tamer E, Shankar, Sharmila, Srivastava, Rakesh K
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474652/ https://www.ncbi.nlm.nih.gov/pubmed/18590557 http://dx.doi.org/10.1186/1476-4598-7-60

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