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Leukemia inhibitory factor promotes human first trimester extravillous trophoblast adhesion to extracellular matrix and secretion of tissue inhibitor of metalloproteinases-1 and -2

BACKGROUND: Leukemia inhibitory factor (LIF) is a pleiotropic cytokine that is essential for blastocyst implantation in mice. It has been suggested that LIF may play a role in human first trimester extravillous trophoblast (EVT) invasion. The aim of the present study was to establish whether LIF ind...

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Detalles Bibliográficos
Autores principales: Tapia, Alejandro, Salamonsen, Lois A., Manuelpillai, Ursula, Dimitriadis, Evdokia
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474668/
https://www.ncbi.nlm.nih.gov/pubmed/18492704
http://dx.doi.org/10.1093/humrep/den121