Viral complementation allows HIV-1 replication without integration

BACKGROUND: The integration of HIV-1 DNA into cellular chromatin is required for high levels of viral gene expression and for the production of new virions. However, the majority of HIV-1 DNA remains unintegrated and is generally considered a replicative dead-end. A limited amount of early gene expr...

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Detalles Bibliográficos
Autores principales: Gelderblom, Huub C, Vatakis, Dimitrios N, Burke, Sean A, Lawrie, Steven D, Bristol, Gregory C, Levy, David N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474848/
https://www.ncbi.nlm.nih.gov/pubmed/18613957
http://dx.doi.org/10.1186/1742-4690-5-60

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