The prognostic value of FISH as an adjunct to conventional cytogenetics for the detection of cryptic gene rearrangements on chromosome 16. A retrospective investigation of 13 patients from Northern Ireland diagnosed with M4Eo acute myeloid leukaemia.

M4Eo acute myeloid leukaemia (AML) patients with the typical chromosome 16 abnormalities have a favourable prognosis. These subtle 16q22 gene rearrangements can be difficult to detect by conventional cytogenetic methods and if missed could lead to the incorrect assignment of prognostic group and hen...

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Detalles Bibliográficos
Autores principales: McGrattan, P., Humphreys, M. W.
Formato: Texto
Lenguaje:English
Publicado: Ulster Medical Society 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475396/
https://www.ncbi.nlm.nih.gov/pubmed/12868698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475396/
https://www.ncbi.nlm.nih.gov/pubmed/12868698

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