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Linkage Disequilibrium-Based Quality Control for Large-Scale Genetic Studies
Quality control (QC) is a critical step in large-scale studies of genetic variation. While, on average, high-throughput single nucleotide polymorphism (SNP) genotyping assays are now very accurate, the errors that remain tend to cluster into a small percentage of “problem” SNPs, which exhibit unusua...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475504/ https://www.ncbi.nlm.nih.gov/pubmed/18670630 http://dx.doi.org/10.1371/journal.pgen.1000147 |