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Structural polymorphism of intramolecular quadruplex of human telomeric DNA: effect of cations, quadruplex-binding drugs and flanking sequences

G-quadruplex structures formed in the telomeric DNA are thought to play a role in the telomere function. Drugs that stabilize the G-quadruplexes were shown to have anticancer effects. The structures formed by the basic telomeric quadruplex-forming unit G(3)(TTAG(3))(3) were the subject of multiple s...

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Detalles Bibliográficos
Autores principales:	Gaynutdinov, Timur I., Neumann, Ronald D., Panyutin, Igor G.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475613/ https://www.ncbi.nlm.nih.gov/pubmed/18535007 http://dx.doi.org/10.1093/nar/gkn351

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