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Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides
The potential use of antisense and siRNA oligonucleotides as therapeutic agents has elicited a great deal of interest. However, a major issue for oligonucleotide-based therapeutics involves effective intracellular delivery of the active molecules. In this Survey and Summary, we review recent reports...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475625/ https://www.ncbi.nlm.nih.gov/pubmed/18558618 http://dx.doi.org/10.1093/nar/gkn342 |