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Development of a single tube 640-plex genotyping method for detection of nucleic acid variations on microarrays
Detection of DNA sequence variation is critical to biomedical applications, including disease genetic identification, diagnosis and treatment, drug discovery and forensic analysis. Here, we describe an arrayed primer extension-based genotyping method (APEX-2) that allows multiplex (640-plex) DNA amp...
Autores principales: | Krjutškov, Kaarel, Andreson, Reidar, Mägi, Reedik, Nikopensius, Tiit, Khrunin, Andrey, Mihailov, Evelin, Tammekivi, Veronika, Sork, Helena, Remm, Maido, Metspalu, Andres |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475630/ https://www.ncbi.nlm.nih.gov/pubmed/18539607 http://dx.doi.org/10.1093/nar/gkn357 |
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