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The N-Terminal Domain of the Drosophila Retinoblastoma Protein Rbf1 Interacts with ORC and Associates with Chromatin in an E2F Independent Manner

BACKGROUND: The retinoblastoma (Rb) tumor suppressor protein can function as a DNA replication inhibitor as well as a transcription factor. Regulation of DNA replication may occur through interaction of Rb with the origin recognition complex (ORC). PRINCIPAL FINDINGS: We characterized the interactio...

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Detalles Bibliográficos
Autores principales:	Ahlander, Joseph, Chen, Xiao-Bo, Bosco, Giovanni
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475671/ https://www.ncbi.nlm.nih.gov/pubmed/18665226 http://dx.doi.org/10.1371/journal.pone.0002831

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