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Mitogen-activated Protein Kinase Phosphatase-1 Represses c-Jun NH(2)-terminal Kinase-mediated Apoptosis via NF-κB Regulation

The mechanism regulating radiation-induced anti-apoptotic response, a limiting factor in improving cell radiosensitivity, remains elusive. Mitogen-activated protein kinase (MAPK) phosphatase (MKP)-1 is the major member of MKPs that dephosphorylates and inactivates MAPK. Here we provide the evidence...

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Detalles Bibliográficos
Autores principales:	Wang, Zhaoqing, Cao, Ning, Nantajit, Danupon, Fan, Ming, Liu, Yusen, Li, Jian Jian
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Mechanisms of Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2475689/ https://www.ncbi.nlm.nih.gov/pubmed/18508759 http://dx.doi.org/10.1074/jbc.M802229200

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